Funk OH, Qalieh Y, Doyle DZ, Lam MM, Kwan KY (2022). Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity. Proc Natl Acad Sci U S A, 119: e2116956119.
Doyle DZ, Lam MM, Qalieh A, Qalieh Y, Sorel A, Funk OH, Kwan KY (2021). Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity. Proc Natl Acad Sci U S A, 118: e2100686118111. PDF
Keil JM, Doyle DZ, Qalieh A, Lam MM, Funk OH, Qalieh Y, Shi L, Mohan N, Sorel A, Kwan KY (2020). Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nature Communications, 11: 3839. PDF
Bott CJ, McMahon LP, Keil JM, Yap CC, Kwan KY, Winckler B (2020). Nestin Selectively Facilitates the Phosphorylation of the Lissencephaly-Linked Protein Doublecortin (DCX) by cdk5/p35 to Regulate Growth Cone Morphology and Sema3a Sensitivity in Developing Neurons. Journal of Neuroscience, 40: 3720-3740.
Zhou W, Emery SB, Flasch DA, Wang Y, Kwan KY, Kidd JM, Moran JV, Mills RE (2020). Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology. Nucleic Acids Research, 48: 1146-1163.
Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY (2019). Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nature Communications, 10: 2588. PDF
Keil JM, Qalieh A, Kwan KY (2018). Brain Transcriptome Databases: A User’s Guide. Journal of Neuroscience, 38: 2399-2412. PDF
McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, Mills RE, Paquola ACM, Rodin RE, Rosenbluh C, Sestan N, Sherman MA, Shin JH, Song S, Straub RE, Thorpe J, Weinberger DR, Urban AE, Zhou B, Gage FH, Lehner T, Senthil G, Walsh CA, Chess A, Courchesne E, Gleeson JG, Kidd JM, Park PJ, Pevsner J, Vaccarino FM; Brain Somatic Mosaicism Network (2017). Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science, 356: eaal1641.
Akins MR, Berk-Rauch HE, Kwan KY, Mitchell ME, Shepard KA, Korsak LI, Stackpole EE, Warner-Schmidt JL, Sestan N, Cameron HA, Fallon JR (2017). Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains. Human Molecular Genetics, 26: 192-209.
Caubit X, Gubellini P, Andrieux J, Roubertoux PL, Metwaly M, Jacq B, Fatmi A, Had-Aissouni L, Kwan KY, Salin P, Carlier M, Liedén A, Rudd E, Shinawi M, Vincent-Delorme C, Cuisset JM, Lemaitre MP, Abderrehamane F, Duban B, Lemaitre JF, Woolf AS, Bockenhauer D, Severac D, Dubois E, Zhu Y, Sestan N, Garratt AN, Lydia Kerkerian-Le Goff, Fasano L (2016). TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons. Nature Genetics, 48: 1359-1369.
Iwase S, Brookes E, Agarwal S, Badeaux AI, Ito H, Vallianatos CN, Tomassy GS, Kasza T, Lin G, Thompson A, Gu L, Kwan KY, Chen C, Sartor MA, Egan B, Xu J, Shi Y (2016). A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation. Cell Reports, 14:1000-1009.
Colvin SM, Kwan KY (2014). Dysregulated nitric oxide signaling as a candidate mechanism of fragile X syndrome and other neuropsychiatric disorders. Frontiers in Genetics, 5: 239. PDF
Funk OH, Kwan KY (2014). Nitric oxide signaling in the development and evolution of language and cognitive circuits. Neuroscience Research, 86: 77-87. PDF
Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Dravis C, Kwan KY, Šestan N, Greenberg ME, Henkemeyer M, Cowan CW (2014). EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding. Proc Natl Acad Sci U S A, 111: 2188-2193.
Kwan KY (2013). Transcriptional dysregulation of neocortical circuit assembly in ASD. International Review of Neurobiology, 113: 167-205. PDF
Shim S, Kwan KY, Li M, Lefebvre V, Sestan N. Cis-regulatory control of corticospinal system development and evolution (2012). Nature, 486: 74-79. PDF
Kwan KY, Lam MMS, Johnson MB, Dube U, Shim S, Rasin MR, Sousa AMM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, Schwartz ML, Willemsen R, Oostra BA, Rakic P, Heffer M, Kostovic I, Judas M, Sestan N (2012). Species-dependent post-transcriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell, 149: 899-911. PDF
Kwan KY, Sestan N, Anton ES (2012). Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex. Development, 139: 1535-1546. PDF
*Barak T, *Kwan KY, Louvi A, Demirbilek V, Saygi S, Tuysuz B, Choi M, Boyaci H, Doerschner K, Zhu Y, Kaymakcalan H, Yilmaz S, Bakircioglu M, Caglayan AO, Ozturk AK, Brunken WJ, Yalcinkaya C, Dincer A, Bronen RA, Mane S, Ozcelik T, Lifton RP, Sestan N, Bilguvar K, Gunel M (2011). Recessive LAMC3 mutations cause malformations of occipital cortical development. Nature Genetics, 43: 590-594. [*equal contributors] PDF
*Han W, *Kwan KY, *Shim S, Lam MMS, Shin Y, Xu X, Zhu Y, Li M, Sestan N (2011). TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract. Proc Natl Acad Sci U S A, 108: 3041-3046. [*equal contributors] PDF
Bilguvar K, Ozturk AK, Louvi A, Kwan KY, Choi M, Tatli B, Yalnizoglu D, Tuysuz B, Caglayan AO, Gokben S, Kaymakcalan H, Barak T, Bakircioglu M, Yasuno K, Ho W, Sanders S, Zhu Y, Yilmaz S, Dincer A, Johnson MH, Bronen RA, Kocer N, Per H, Mane S, Pamir MN, Yalcinkaya C, Kumandas S, Topcu M, Ozmen M, Sestan N, Lifton RP, State MW, Gunel M (2010). Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature, 467: 207-210. PDF
Fertuzinhos S, Krsnik Z, Imamura Kawasawa Y, Rasin MR, Kwan KY, Chen JG, Judas M, Hayashi M, Sestan N (2009). Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia. Cereb Cortex, 19: 2196-2207. PDF
*Kwan KY, *Lam MMS, Krsnik Z, Imamura Kawasawa Y, Lefebvre V, Sestan N (2008). SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons. Proc Natl Acad Sci U S A, 105: 16021-16026. [*equal contributors] PDF
Britanova O, de Juan Romero C, Cheung A, Kwan KY, Schwark M, Gyorgy A, Vogel T, Akopov S, Mitkovski M, Agoston D, Sestan N, Molnar Z, Tarabykin V (2008). Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Neuron, 57: 378-392. PDF
Rasin MR, Gazula V, Breunig J, Kwan KY, Johnson MB, Liu-Chen S, Li H, Jan L, Jan Y, Rakic P, Sestan N (2007). Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nature Neuroscience, 10: 819-827. PDF
Chen JG, Rasin MR, Kwan KY, Sestan N (2005). Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex. Proc Natl Acad Sci U S A, 102: 17792-17797. PDF
*Abelson JF, *Kwan KY, *O’Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LSt, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW (2005). Sequence variants in SLITRK1 are associated with Tourette’s syndrome. Science, 310: 317-320. [*equal contributors] PDF
Hegele RA, Kwan K, Harris SB, Hanley AJ, Zinman B, Cao H (2000). NAT2 polymorphism associated with plasma glucose concentration in Canadian Oji-Cree. Pharmacogenetics, 10: 233-238.