Publications


  1. Shim S, Kwan KY, Li M, Lefebvre V, Sestan N. Cis-regulatory control of corticospinal system development and evolution (2012). Nature, 486: 74-79. PDF

  2. Kwan KY, Lam MMS, Johnson MB, Dube U, Shim S, Rasin MR, Sousa AMM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, Schwartz ML, Willemsen R, Oostra BA, Rakic P, Heffer M, Kostovic I, Judas M, Sestan N (2012). Species-dependent post-transcriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell, 149: 899-911. PDF

  3. Kwan KY, Sestan N, Anton ES (2012). Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex. Development, 139: 1535-1546. PDF

  4. *Barak T, *Kwan KY, Louvi A, Demirbilek V, Saygi S, Tuysuz B, Choi M, Boyaci H, Doerschner K, Zhu Y, Kaymakcalan H, Yilmaz S, Bakircioglu M, Caglayan AO, Ozturk AK, Brunken WJ, Yalcinkaya C, Dincer A, Bronen RA, Mane S, Ozcelik T, Lifton RP, Sestan N, Bilguvar K, Gunel M (2011). Recessive LAMC3 mutations cause malformations of occipital cortical development. Nature Genetics, 43: 590-594. [*equal contributors] PDF

  5. *Han W, *Kwan KY, *Shim S, Lam MMS, Shin Y, Xu X, Zhu Y, Li M, Sestan N (2011). TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract. Proc Natl Acad Sci U S A, 108: 3041-3046. [*equal contributors] PDF

  6. Bilguvar K, Ozturk AK, Louvi A, Kwan KY, Choi M, Tatli B, Yalnizoglu D, Tuysuz B, Caglayan AO, Gokben S, Kaymakcalan H, Barak T, Bakircioglu M, Yasuno K, Ho W, Sanders S, Zhu Y, Yilmaz S, Dincer A, Johnson MH, Bronen RA, Kocer N, Per H, Mane S, Pamir MN, Yalcinkaya C, Kumandas S, Topcu M, Ozmen M, Sestan N, Lifton RP, State MW, Gunel M (2010). Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature, 467: 207-210. PDF

  7. Fertuzinhos S, Krsnik Z, Imamura Kawasawa Y, Rasin MR, Kwan KY, Chen JG, Judas M, Hayashi M, Sestan N (2009). Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia. Cereb Cortex, 19: 2196-2207. PDF

  8. *Kwan KY, *Lam MMS, Krsnik Z, Imamura Kawasawa Y, Lefebvre V, Sestan N (2008). SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons. Proc Natl Acad Sci U S A, 105: 16021-16026. [*equal contributors] PDF

  9. Britanova O, de Juan Romero C, Cheung A, Kwan KY, Schwark M, Gyorgy A, Vogel T, Akopov S, Mitkovski M, Agoston D, Sestan N, Molnar Z, Tarabykin V (2008). Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Neuron, 57: 378-392. PDF

  10. Rasin MR, Gazula V, Breunig J, Kwan KY, Johnson MB, Liu-Chen S, Li H, Jan L, Jan Y, Rakic P, Sestan N (2007). Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nature Neuroscience, 10: 819-827. PDF

  11. Chen JG, Rasin MR, Kwan KY, Sestan N (2005). Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex. Proc Natl Acad Sci U S A, 102: 17792-17797. PDF

  12. *Abelson JF, *Kwan KY, *O’Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LSt, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW (2005). Sequence variants in SLITRK1 are associated with Tourette’s syndrome. Science, 310: 317-320. PDF

  13. Hegele RA, Kwan K, Harris SB, Hanley AJ, Zinman B, Cao H (2000). NAT2 polymorphism associated with plasma glucose concentration in Canadian Oji-Cree. Pharmacogenetics, 10: 233-238.